CEFIXIME & LACTIC ACID BACILLUS TABLETS

FYCEF-LB is a combination of two medicines: Cefixime and Lactic Acid Bacillus Tablets used in the therapy of bacterial infections. Cefixime belongs to the drug range of antibiotics and it helps by inhibiting the formation of the bacterial shielding covering which is necessary for the durability of bacteria in the human body. Lactobacillus is a live micro-organism drug that rebuilds the balance of good bacteria in the stomach that may get unsettled with antibiotic use or due to intestinal viruses.

Cefixime and Lactic Acid Bacillus Tablets are usually prescribed to children to handle a wide variety of bacterial infections targeting the ear, eyes, gastrointestinal tract, nose, throat, lungs, skin, and urinary tract.

Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases may be susceptible to cefixime. The antibacterial effect of cefixime results from the inhibition of mucopeptide synthesis in the bacterial cell wall.

Precaution for Cefixime and Lactic Acid Bacillus Tablets

Inform the doctor if the patient has any history of allergy, heart problem, blood disorder, gastrointestinal problem, skin disorder, airway obstruction, lung anomaly, liver impairment, and kidney breakdown. This knowledge is important for dose adjustments and the doctor will prescribe the right dose and duration for Cefixime and Lactic Acid Bacillus Tablets according to the patient condition and symptoms.

Side Effects of Cefixime and Lactic Acid Bacillus Tablets

Cefixime and Lactic Acid Bacillus Tablets may cause minor and short side effects such as vomiting, diarrhea, nausea, abdominal pain, and allergy to the patient. Usually, these incidents subside once the patient’s body adapts to the medicine. However, if these side effects persist or become bothersome then consult the doctor.

PHARMACODYNAMICS: – Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.
• Absorption: – About 40%-50% absorbed orally whether administered with or without food, however, time to maximal absorption is increased approximately 0.8 hours when administered with food.
• Protein binding: – 65% (concentration independent)
• Metabolism: – Hepatic. Approximately 50% of the absorbed dose is excreted unchanged in the urine in 24 hours.
• Half-life: – 3-4 hours (may range up to 9 hours). In severe renal impairment (5 to 20 mL/min creatinine clearance), the half-life increased to an average of 11.5 hours.

INDICATION:- For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms:
(1) uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis,
(2) otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-lactamase positive), and S. pyogenes,
(3) pharyngitis and tonsillitis caused by S. pyogenes,
(4) acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (beta-lactamase positive and negative strains), and (5) uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae (penicillinase- and non-penicillinase-producing strains).

Contact Us for Manufacturing and Supply for Cefixime and Lactic Acid Bacillus Tablets

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